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Does CBD for Joint Pain Work?

Does CBD help joint pain? What the research says about CBD for arthritis and achy joints, how CBD works, and other ways to find relief from joint pain.

Woman holding her sore knee, highlighted in red, beside a cannabis leaf and open jars of cream
  1. What is CBD Oil?
  2. How Does CBD Work?
  3. How Can CBD Help?
  4. CBD Works Slowly
  5. Finding Immediate Relief for Joint Pain
  6. Frequently asked questions
  7. Sources

Key Takeaways

  • There is limited scientific evidence that CBD eases joint pain, and there have been no rigorous clinical studies of CBD in people with arthritis.
  • The only FDA-approved CBD product is a prescription medicine for certain rare seizure disorders, so CBD is not an approved treatment for joint pain or arthritis.
  • About one in five U.S. adults has diagnosed arthritis, so see a doctor about recurring joint pain without a clear cause.
  • Ibuprofen and acetaminophen are best kept for occasional use, and topical pain relievers work at the site of the pain but should be used only as directed.

CBD became a wildly popular wellness tool, with many people incorporating CBD into their daily rituals the same way they’d incorporate a multivitamin or a cup of coffee. There are many reasons why people use CBD. 

Some of those reasons are vague, some of those reasons are specific, and many of those reasons don’t seem to make sense. How can something promote better sleep while increasing mental energy, supporting athletic performance, and easing discomfort associated with arthritis?

It seems like CBD can do everything, but research supports far fewer uses than people claim. The only FDA-approved CBD product is a prescription medicine for certain rare seizure disorders, and research on other uses is still limited. 

What is CBD Oil?

CBD oil is an extract from the hemp plant. Hemp is a very low THC form of cannabis. Other than the average THC content, hemp and cannabis are similar. 

Many people looking to incorporate cannabis wellness products into their routines opt for hemp products due to the fact that they impart their benefits without cognitive impairment. In other words, hemp doesn’t get you high. 

CBD oil is rich in cannabidiol, a cannabinoid that naturally occurs in all cannabis plants. Cannabidiol is often used as a supplement to temporarily support the overall wellness of the human body holistically. It works by interacting with the body’s endocannabinoid system to support a wide array of processes.

How Does CBD Work?

The body is full of cannabinoid receptors, broadly referred to as the endocannabinoid system. These receptors play a role in most of the major processes that take place within the body.

The human body produces its own chemicals called cannabinoids, called endocannabinoids, to stimulate the system.

Researchers still haven’t mastered the specifics of endocannabinoid production. It’s hard to tell how much of each endocannabinoid the body needs and exactly what they’re used for because they’re immediately released and utilized.

The theory behind CBD is that it stimulates the system in a way similar to endocannabinoids. It interacts with the endocannabinoid system as that system works to ease emotional and physical tension and stress, support the immune system, and promote regular gastrointestinal health in addition to many other functions. 

CBD doesn’t necessarily act as a medication, as many people expect it would. CBD doesn’t supersede your body’s ability to do the things it’s designed to do. It’s simply a helping hand that supports your body in the routine task of maintenance. 

How Can CBD Help?

CBD isolates, edibles, and extracts can work to ease physical and emotional tension throughout the body. Stress can exacerbate the symptoms of chronic pain, rheumatoid arthritis, or other conditions that impact the muscles and joints. CBD may help some people with joint pain feel a little more at ease by promoting a better mood and supporting overall well-being.

CBD also communicates with the systems in your body responsible for promoting immune system response and inflammatory response. 

Although CBD is not directly an immunity supplement or an anti-inflammatory supplement, it can often be used in conjunction with approved treatments or supplements for this purpose. 

If your joint pain is keeping you up at night, topical CBD, such as CBD creams, balms, salves, and lotions, may be a partial solution. Additionally, many people who use CBD oil tinctures find it easier to unwind at bedtime. It’s always easier to get better quality sleep when you’re fully relaxed. 

CBD Works Slowly

If you’ve tried CBD to no avail, there may be a simple explanation for that. Some studies involving CBD use for targeted purposes have produced encouraging results, but those studies don’t take place in a day. Most of the results are recorded between four weeks and ten weeks of daily use.

CBD results depend on potency, consistency, and proper dosing. It may help to support relief, but it won’t be an immediate solution. It’s best to use CBD in conjunction with a product designed to meet your immediate needs. Your long-term well-being is just as important as your immediate well-being. Making choices to benefit them simultaneously and sticking to those choices is the beginning of a long and rewarding wellness journey. 

Finding Immediate Relief for Joint Pain

CBD isn’t right for everyone, because it can cause side effects and interact with other medicines. With your doctor’s approval, it can safely be incorporated into many daily wellness routines. However, it requires sufficient time to provide adequate relief from symptoms. It’s best to think of CBD as a second line of relief.

People living with joint pain also require immediate relief when aches begin. When joint pain is actively affecting you, here’s what you can do to ease your symptoms.

Talk to Your Doctor About Joint Pain

If you have recurring joint pain without a clear cause, you need to speak to your doctor and be examined for joint disease. It’s important to explore possibilities like arthritis if you haven’t already been diagnosed with the condition that impacts your joint health. 

About one in five U.S. adults has diagnosed arthritis. Planning a visit with your doctor to discuss your options should be your first step.

Use Over-the-Counter Drugs Sparingly

Many people use over-the-counter pain relievers like acetaminophen and ibuprofen for relief from breakthrough pain and inflammation. Using these pain relievers occasionally won’t pose a problem for most people, but frequent use can have adverse side effects.

Ibuprofen can damage the stomach lining, and acetaminophen can cause liver damage. Using these drugs as a daily long-term solution for pain is inadvisable. These medications don’t work directly at the source of the pain. 

They impact the entire body, whether or not they need to, and they can have drug interactions. Why medicate your whole body when you’re seeking localized relief?

Choose Topicals for Targeted Relief

Topicals address joint pain at the source. They’re applied to the skin surrounding the achy joint. A little massage encourages them to penetrate the top layer of the skin, providing cooling and soothing relief to the joint.

Topicals should be used only as directed on the label. One application usually provides relief for several hours. The combination of soothing ingredients in topical creams can go a long way to improve the way your aching joints feel. 

You can use topicals in conjunction with full-spectrum or broad-spectrum CBD products. Check with your doctor first, because CBD can interact with other medicines. 

Frequently asked questions

Can CBD replace arthritis medication?

No. The Arthritis Foundation says CBD should never be used to replace the disease-modifying drugs that help prevent permanent joint damage. The FDA also warns that unproven claims about CBD may lead people to put off proper diagnosis and treatment. Keep taking the medicines your doctor prescribed, and ask before adding CBD.

How do you choose a quality CBD product?

Buy from a company that has each batch tested by an independent lab and provides a certificate of analysis, as the Arthritis Foundation advises. Labels are not always accurate. In a Johns Hopkins study of 105 topical CBD products, only 24% of those that listed a CBD amount were labeled accurately, and 35% of all the products contained THC.

Can CBD cause liver damage?

It can. The FDA says CBD can cause liver injury, and NCCIH notes that CBD use has been linked to abnormal results on liver function tests. The FDA also says it isn't yet known what level of CBD intake triggers these risks. If you use CBD, tell your doctor so they can watch for liver problems.

Does CBD cream work for arthritis?

It hasn't been proven. Harvard Health describes an animal study suggesting CBD applied to the skin could lower arthritis pain and inflammation, but the Arthritis Foundation says there have been no rigorous clinical studies in people with arthritis. A Johns Hopkins study of topical CBD products also noted that the FDA has not approved CBD products to treat any of the conditions they advertised.

Sources & references

  1. Arthritis Foundation. “Arthritis Foundation CBD Guidance for Adults with Arthritis.” Arthritis Foundation, 2024. arthritis.org
  2. U.S. Food and Drug Administration. “What You Need to Know (And What We're Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD.” U.S. Food and Drug Administration, 2020. fda.gov
  3. U.S. Food and Drug Administration. “FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD).” U.S. Food and Drug Administration, 2024. fda.gov
  4. Mayo Clinic Staff. “CBD: Safe and effective?.” Mayo Clinic, 2022. mayoclinic.org
  5. National Center for Complementary and Integrative Health. “Cannabis (Marijuana) and Cannabinoids: What You Need To Know.” NCCIH, 2019. nccih.nih.gov
  6. Grinspoon P. “Cannabidiol (CBD): What we know and what we don't.” Harvard Health Publishing, 2024. health.harvard.edu
  7. Johns Hopkins Medicine. “Study Shows Widespread Mislabeling of CBD Content Occurs for Over-the-Counter Products.” Johns Hopkins Medicine, 2022. hopkinsmedicine.org
  8. “Dosage, Efficacy and Safety of Cannabidiol Administration in Adults: A Systematic Review of Human Trials.” Journal of Clinical Medicine Research, 2020. dx.doi.org
  9. Fallon EA, Boring MA, Foster AL, et al.. “Prevalence of Diagnosed Arthritis — United States, 2019–2021.” MMWR Morbidity and Mortality Weekly Report, 2023. cdc.gov
  10. Vučković S, Srebro D, Savić Vujović K, et al.. “Cannabinoids and Pain: New Insights From Old Molecules.” Frontiers in Pharmacology, 2018. frontiersin.org
  11. U.S. Food and Drug Administration. “FDA Drug Safety Communication: Rare cases of serious burns with the use of over-the-counter topical muscle and joint pain relievers.” U.S. Food and Drug Administration, 2012. fda.gov

Staff Writer

The Hempvana editorial team writes practical, source-backed guides on everyday pain relief, topical ingredients and healthy movement.

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